Chlamydia Trachomatis Treatment – Antibiotics

Chlamydia trachomatis treatment is undertaken through the use of antibiotics as the first line of treatment. In extreme cases however, surgery may be undertaken to rectify any damage caused by the disease, as in the case of epididymitis.

Antibiotics – Chlamydia Trachomatis Treatment

Ideally, anti-bacterial treatment should only be undertaken after the infecting organism has been identified through tests and results of known.

Long-term or repeated administration of antibiotics can lead to super-infections with resistant bacteria or yeast-like fungi. Patients taking antibiotics and simultaneously having diarrhoea should be under close medical care.

Chlamydia Trachomatis Treatment - Antibiotics

The most common and effective antibiotics used in the treatment of chlamydia trachomatis are:

  • Azythromycin – Azythromycin is a macrolide used in the treatment of STD infections by susceptible organisms (chlamydia trachomatis included), mild to moderate upper and lower respiratory tract infections and uncomplicated skin and soft tissue infections. It acts through bacteriostatic or bactericidal mechanism. Azythromycin should be administered 2 hours before eating food or taking antacids or 1 hour after eating or taking antacids. For the treatment of chlamydia trachomatis, it should be taken orally 1g initial dose followed by 500mg once a day dosage for between 7 – 10 days. It is unsuitable for use by pregnant women and lactating mothers. Azythromycin’s side effects include hearing impairment, allergic reactions, chest pain, palpitation, vaginitis and super infections. These side effects however wear off on completion of the dosage. Azythromycin is commercially available by different trade names in dosages of 500mg, 250mg, suspensions in 15ml and 30ml.
  • Erythromycin – Erythromycin is a macrolide used as an alternative for penicillin-allergic patients. It is administered for the treatment of intestinal ameobiasis, chlamdia trachomatis, UTI, skin and soft tissue infections, male gonococcal urethritis and female pelvic infections, syphilis and tetanus. Erythromycin is unsuitable for use by lactating mothers and women in their first trimester pregnancy. In adults, the dosage is 500mg four times a day for seven days. For children above 8 years, the dosage is 250mg four times a day for 7 days. Erythromycin’s side effects include GI disturbances, allergic reactions, hearing loss, super infections, fever and pancreatitis. These side effects however wear off on completion of the dosage. Erythromycin is commercially available by different trade names in 60ml, 100ml, 250mg and 500mg.
  • Doxycycline – Doxycycline acts by inhibiting protein synthesis of susceptible bacteria thereby preventing cell replication. It is administered for the treatment of Rocky Mountain spotted fever, typhus fever, respiratory tract infections, trachoma caused by chlamydia trachomatis and many other bacterial infections. Doxycyclin is unsuitable for use by lactating mothers, pregnant women and children below the age of 12 years. Its dosage is 200mg STAT followed by 100mg once daily for 7 days. It is available commercially in 100mg capsules. Doxycycline’s side effects include super infections, tooth discolouration, photosensitivity, nail discolouration and GI disturbances. These however wear off on completion of the dosage.

Although these antibiotic drugs can effectively treat and cure chlamydia trachomatis, prevention is the best cure. Prevention can be undertaken through education and counselling of those at risk on safe sexual behaviour. Effective diagnosis and treatment of those infected is also important to avoid re-occurrence.

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