Haemophilus Influenza was discovered back in 1892 when there was an Influenza pandemic. Richard Pfeiffer who discovered this type of Influenza found out that Haemophilus Influenza was the first free-living organism to have its entire genome sequenced.
Haemophilus Influenza has is classified under two categories; Encapsulated strains; these strains have been grouped by the basis of their distinct capsular antigens.
These groups are six and they range from a-f. Unencapsulated strains; these are known as nontypable (NTHi) since they lack capsular serotypes; but, they can are also grouped by multilocus sequence typing.
Haemophilus Influenza Infections
Haemophilus Influenza has never been full understood up to date as much as the occurrence of the capsule in encapsulated type b (Hib), a serotype instigating infections such as epiglottitis, is known to be a major factor in virulence.
This occurs since the capsule permits them to fight phagocytosis and complement-mediated lysis in the non-immune host. But the unencapsulated strains are nearly every time less aggressive; they can, however, create a seditious response in humans, which always lead to a variety of symptoms.
Strains emanating from Haemophilus Influenza know how to exist in a persons’ body without being known, since they will live in the person for ages without causing trouble. The only time the strains rake in trouble is when your immune systems is low, you suddenly get allergies or you suffer from a viral infection, under these circumstances, the influenza strains take advantage and start causing trouble.
Acute bacteria meningitis, pneumonia and bacteremia are some of the diseases that appear in young children whose causes are majorly associated with Haemophilus Influenza type b (Hib). Other types of diseases caused by Haemophilus Influenza include:
- Infectious arthritis
Sadly though, in developed countries where Haemophilus Influenza vaccination is rare, children suffer from ear infections, eye infections and sinusitis and off-course it is a major cause of pneumonia.
Haemophilus Influenza Treatment
Ideally, Haemophilus Influenza type b (Hib) infections are best treated with an intravenous third-generation cephalosporin, this however was done so until antibiotic sensitivities become available. To put it in short, the size of the infection determines the period length that the antibiotic dosage will be administered.
Antibiotics such as amoxicillin and ampicillin should only be administered after the lab tests have confirmed their potency. For high infection of Haemophilus influenza like infection in lungs, brain, bloodstream and bone need endovenous administration of 3rd generation ceftriaxone, cephalosporin and ciprofloxacin or cefotaxime for 10 -14 days.
Side effects: Like all drugs, antibiotics also come with their own share of side effects that include:
- Red skin rashes
To successfully rid of respiratory tract contagion caused by Haemophilus Influenza, antibiotics such as cephalosporin and fluoroquinolone in compounding with macrolides like erythromycin, or azithromycin are heavily recommended.
Oxygen therapy is often given to patients who are having Haemophilus influenza infections in lungs and bloodstream that induce shortness of breath plus disorientation, this process is done via tubes passed through the nose hole or a mask that is used to cover the mouth and nose area and the patients breathe in and out in it.